The Comotomo Natural Feel is the only mainstream baby bottle whose body is made entirely from medical-grade silicone, the same material as the nipple. That matters because breastfed babies who reject other bottles are usually rejecting the hard plastic body, not just the nipple. When a baby grips a Comotomo, they feel the same soft, skin-like material they associate with nursing. BabyGearLab tested nipple acceptance rates across bottles and ranked Comotomo highest by a wide margin.


The ultra-wide neck is the second differentiator. It is physically large enough to fit an adult hand inside for thorough cleaning, which no narrow-neck bottle allows. That clears out the residue buildup in bottle base corners that brushes fail to reach over repeated washing. Both Mommyhood101 and BabyGearLab called out this cleaning feature as a real daily-use advantage.
The dual anti-colic vents handle most gas cases well enough. For the majority of parents, meaning those without a baby diagnosed with severe colic, the Comotomo offers enough anti-colic performance alongside better nipple acceptance and easier cleaning to earn the overall win. Mommyhood101 noted that it has 'slowly climbed into the top spot' over three years of testing as their top recommendation across multiple baby age groups.
What It Won't Do
The Comotomo has one functional weakness: getting a leak-free seal is harder than with narrow-neck bottles. The wide silicone gasket has to be seated correctly to prevent drips, a small learning curve that catches some parents off guard, particularly at 3 am. BabyGearLab flagged this as the bottle's main technical complaint. The translucent silicone also makes volume markings hard to read. For parents on a pediatrician's feeding plan who need precise intake measurements, that is a real limitation. The soft body warms more slowly in a bottle warmer too, because silicone insulates better than plastic.
Dr. Brown's Natural Flow Options+ is the most clinically validated bottle in this review. Its patented two-piece internal vent system, made up of a reservoir tube and vent insert, creates positive-pressure flow that eliminates the vacuum (negative pressure) that normally forms during feeding. Without that vacuum, babies don't have to suck harder to keep the milk coming, so they swallow far less air. Pediatricians and lactation consultants recommend Dr. Brown's specifically for diagnosed colic and reflux.


The Options+ design adds real flexibility: the vent system comes out once a baby outgrows colic around 3-4 months, turning the bottle into a simpler one for daily use. Glass versions are available for parents who prefer no plastic in the milk path. At $5 per bottle in the 4-pack format, it is the best price per bottle among the reviewed picks.
For parents whose main worry is gas and colic rather than nipple transition or nipple confusion, Dr. Brown's anti-colic performance is unmatched.
What It Won't Do
The five-piece disassembly (bottle body, collar, reservoir, vent insert, nipple) is the Options+'s most-cited complaint. Reviewed.com and Mommyhood101 both flagged the extra parts as a heavy daily-use burden when you are washing 8+ bottles a day in the newborn stage. The narrower nipple shape is the second real limitation. Breastfed babies who switch between breast and bottle regularly reject the Dr. Brown's nipple at higher rates than they do Comotomo or Tommee Tippee. For mixed-feeding families, the narrow nipple simply does not match the wide latch babies learn at the breast.
Who Should Buy Which
Comotomo Natural Feel Baby Bottle (5oz, 2-Pack)
The squeezable silicone bottle with a breast-like nipple that breastfed babies accept without a fight
- Breastfed babies being introduced to bottle feeds, because the soft silicone body and wide nipple base replicate breast skin texture and contact area and reduce nipple confusion
- Parents who put thorough cleaning first, since the ultra-wide neck lets you hand-clean without a brush and clear the residue that bottle brushes miss in the corners
- Families who want a single bottle for the entire first year, since the same Comotomo body works from newborn through toddler with flow nipple upgrades
- Parents whose babies have shown nipple rejection or fussiness with standard plastic bottles
- Anyone who prefers medical-grade silicone over plastic in the milk path without switching to heavier glass
Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack)
The gold standard anti-colic bottle with a patented vent system that eliminates negative pressure from every feed
- Newborns and infants with confirmed colic, gas, or reflux, since Dr. Brown's is the clinical gold standard for anti-colic performance and the bottle pediatricians recommend first
- Parents bottle-feeding from birth without breastfeeding transition concerns who want maximum gas prevention at the lowest per-bottle cost
- Families with preemies who need the ultra-slow Level 1 nipple for controlled feeding
- Parents who want glass bottles, since the Options+ glass version is widely available and uses the same full vent system
- Budget-conscious parents buying a full bottle wardrobe: at $5 per bottle, a complete 6-bottle set costs under $30