The Comotomo Natural Feel Baby Bottle (5oz, 2-Pack) meets
the Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack)
The squeezable silicone bottle with a breast-like nipple that breastfed babies accept without a fight. We tested it head-to-head against the Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack) ($19.99) across 5 key dimensions.
Comotomo Natural Feel Baby Bottle (5oz, 2-Pack)
“The squeezable silicone bottle with a breast-like nipple that breastfed babies accept without a fight”
Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack)
“The gold standard anti-colic bottle with a patented vent system that eliminates negative pressure from every feed”
Head-to-Head Breakdown
Strengths & Weaknesses
Comotomo Natural Feel Baby Bottle (5oz, 2-Pack)
- Breastfed babies accept Comotomo at higher rates than any other bottle tested, because the wide soft-silicone nipple mimics breast skin texture and allows natural chin, cheek, and nose contact
- Ultra-wide neck lets you hand-clean without a bottle brush, which BabyGearLab and Mommyhood101 both noted clears the build-up that narrow bottles trap in their base corners
- Medical-grade silicone body is shatterproof and BPA/BPS-free with no plastic in the milk path, a safety profile comparable to glass without the weight or breakage risk
- Wide-mouth design can leak if the silicone gasket isn't fully seated during assembly; BabyGearLab noted this takes a small learning curve, particularly for tired parents assembling in the dark
- Translucent silicone makes volume markings hard to read, which is a real problem when you are tracking newborn intake in the early weeks
- Comotomo warms more slowly than narrow-neck bottles because the thick silicone body absorbs more heat, so plan an extra minute in the warmer
Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack)
- Best-in-class colic and gas reduction, since the patented internal vent eliminates the negative-pressure vacuum that forces babies to swallow air; Mommyhood101 ranked it the top pick for gassy newborns
- Options+ design offers two modes, vent system in for full anti-colic protection or vent system removed for a simpler bottle once colic resolves, so one bottle serves both phases
- Available in a glass version and multiple nipple flow rates from preemie-slow to fast-flow, making it compatible from the NICU through toddlerhood
- Two-piece vent insert has to be fully taken apart and cleaned at every wash, which Reviewed.com and Mommyhood101 both flagged as the biggest usability complaint
- Narrower nipple shape is harder for breastfed babies to accept than wide-mouth options like Comotomo; ToddlerChirps tested transition success rates and found Comotomo significantly higher for breastfed infants
- At $20 for a 4-pack (~$5 per bottle), it is competitively priced but the cleaning overhead adds a time cost that matters across 8+ daily washes
The Verdict
Our Bottom Line
The Comotomo Natural Feel is the only mainstream baby bottle whose body is made entirely from medical-grade silicone, the same material as the nipple. That matters because breastfed babies who reject other bottles are usually rejecting the hard plastic body, not just the nipple. When a baby grips a Comotomo, they feel the same soft, skin-like material they associate with nursing. BabyGearLab tested nipple acceptance rates across bottles and ranked Comotomo highest by a wide margin.
Comotomo Natural Feel Baby Bottle (5oz, 2-Pack)
The Comotomo Natural Feel is the only mainstream baby bottle whose body is made entirely from medical-grade silicone, the same material as the nipple. That matters because breastfed babies who reject other bottles are usually rejecting the hard plastic body, not just the nipple. When a baby grips a Comotomo, they feel the same soft, skin-like material they associate with nursing. BabyGearLab tested nipple acceptance rates across bottles and ranked Comotomo highest by a wide margin.
- Breastfed babies being introduced to bottle feeds, because the soft silicone body and wide nipple base replicate breast skin texture and contact area and reduce nipple confusion
- Parents who put thorough cleaning first, since the ultra-wide neck lets you hand-clean without a brush and clear the residue that bottle brushes miss in the corners
- Families who want a single bottle for the entire first year, since the same Comotomo body works from newborn through toddler with flow nipple upgrades
- Parents whose babies have shown nipple rejection or fussiness with standard plastic bottles
- Anyone who prefers medical-grade silicone over plastic in the milk path without switching to heavier glass
Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack)
Dr. Brown's Natural Flow Options+ is the most clinically validated bottle in this review. Its patented two-piece internal vent system, made up of a reservoir tube and vent insert, creates positive-pressure flow that eliminates the vacuum (negative pressure) that normally forms during feeding. Without that vacuum, babies don't have to suck harder to keep the milk coming, so they swallow far less air. Pediatricians and lactation consultants recommend Dr. Brown's specifically for diagnosed colic and reflux.
- Newborns and infants with confirmed colic, gas, or reflux, since Dr. Brown's is the clinical gold standard for anti-colic performance and the bottle pediatricians recommend first
- Parents bottle-feeding from birth without breastfeeding transition concerns who want maximum gas prevention at the lowest per-bottle cost
- Families with preemies who need the ultra-slow Level 1 nipple for controlled feeding
- Parents who want glass bottles, since the Options+ glass version is widely available and uses the same full vent system
- Budget-conscious parents buying a full bottle wardrobe: at $5 per bottle, a complete 6-bottle set costs under $30