The Comotomo Natural Feel Baby Bottle (5oz, 2-Pack) meets
the Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack)
The squeezable silicone bottle with a breast-like nipple that breastfed babies accept without a fight. We tested it head-to-head against the Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack) ($19.99) across 5 key dimensions.
Comotomo Natural Feel Baby Bottle (5oz, 2-Pack)
“The squeezable silicone bottle with a breast-like nipple that breastfed babies accept without a fight”
Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack)
“The gold standard anti-colic bottle with a patented vent system that eliminates negative pressure from every feed”
Head-to-Head Breakdown
Strengths & Weaknesses
Comotomo Natural Feel Baby Bottle (5oz, 2-Pack)
- Breastfed babies accept Comotomo at higher rates than any other bottle tested — the wide soft-silicone nipple mimics breast skin texture and allows natural chin, cheek, and nose contact
- Ultra-wide neck allows hand cleaning without a bottle brush — BabyGearLab and Mommyhood101 both noted this eliminates the build-up that narrow bottles harbor in their base corners
- Medical-grade silicone body is shatterproof and BPA/BPS-free with no plastic in the milk path — a safety profile comparable to glass without the weight or breakage risk
- Wide-mouth design can leak if the silicone gasket isn't fully seated during assembly — BabyGearLab noted this requires a small learning curve, particularly for tired parents assembling in the dark
- Translucent silicone makes volume markings difficult to read — especially a problem when tracking newborn intake in the early weeks
- Comotomo's gentle warming time is slower than narrow-neck bottles because the thick silicone body absorbs more heat — plan an extra minute in the warmer
Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack)
- Best-in-class colic and gas reduction — the patented internal vent eliminates the negative-pressure vacuum that forces babies to swallow air; Mommyhood101 ranked it the top pick for gassy newborns
- Options+ design offers two modes: vent system in (full anti-colic protection) or vent system removed (simpler bottle once colic resolves) — one bottle serves both phases
- Available in a glass version and multiple nipple flow rates from preemie-slow to fast-flow, making it compatible from the NICU through toddlerhood
- Two-piece vent insert requires full disassembly and cleaning at every wash — Reviewed.com and Mommyhood101 both flagged the extra parts as the biggest usability complaint
- Narrower nipple shape is harder for breastfed babies to accept than wide-mouth options like Comotomo; ToddlerChirps tested transition success rates and found Comotomo significantly higher for breastfed infants
- At $20 for a 4-pack (~$5 per bottle), it is competitively priced but the cleaning overhead adds a time cost that matters across 8+ daily washes
The Verdict
Our Bottom Line
The Comotomo Natural Feel bottle is the only mainstream baby bottle whose body is made entirely from medical-grade silicone — the same material as the nipple. This is meaningful because breastfed babies who reject other bottles are typically rejecting the hard plastic body, not just the nipple. When a baby grips a Comotomo, they feel the same soft, skin-like material they associate with nursing. BabyGearLab tested nipple acceptance rates across bottles and ranked Comotomo highest by a significant margin.
Comotomo Natural Feel Baby Bottle (5oz, 2-Pack)
The Comotomo Natural Feel bottle is the only mainstream baby bottle whose body is made entirely from medical-grade silicone — the same material as the nipple. This is meaningful because breastfed babies who reject other bottles are typically rejecting the hard plastic body, not just the nipple. When a baby grips a Comotomo, they feel the same soft, skin-like material they associate with nursing. BabyGearLab tested nipple acceptance rates across bottles and ranked Comotomo highest by a significant margin.
- Breastfed babies being introduced to bottle feeds — the soft silicone body and wide nipple base replicate breast skin texture and contact area, reducing nipple confusion
- Parents who prioritize thorough cleaning — the ultra-wide neck allows direct hand-cleaning without a brush, eliminating residue in corners that bottle brushes miss
- Families who want a single bottle for the entire first year — the same Comotomo body works from newborn through toddler with flow nipple upgrades
- Parents whose babies have shown nipple rejection or fussiness with standard plastic bottles
- Anyone who prefers medical-grade silicone over plastic in the milk path without switching to heavier glass
Dr. Brown's Natural Flow Anti-Colic Options+ Baby Bottle (8oz, 4-Pack)
Dr. Brown's Natural Flow Options+ is the most clinically validated bottle in this review. Its patented two-piece internal vent system — consisting of a reservoir tube and vent insert — creates positive-pressure flow that eliminates the vacuum (negative pressure) that normally forms during feeding. Without that vacuum, babies don't need to suck harder to maintain flow, which means they ingest far less air. Pediatricians and lactation consultants specifically recommend Dr. Brown's for diagnosed colic and reflux.
- Newborns and infants with confirmed colic, gas, or reflux — Dr. Brown's is the clinical gold standard for anti-colic performance that pediatricians recommend first
- Parents bottle-feeding from birth without breastfeeding transition concerns who want maximum gas prevention at the lowest per-bottle cost
- Families with preemies who need the ultra-slow Level 1 nipple for controlled feeding
- Parents who want glass bottles — the Options+ glass version is widely available and uses the same full vent system
- Budget-conscious parents buying a full bottle wardrobe — at $5 per bottle, a complete 6-bottle set costs under $30